Iso-butomidate is an anesthetic drug related to etomidate, which has been sold as a designer drug as an active ingredient in e-cigarette liquids marketed under names such as space oil or kpods. It has an iso-butyl ester group in place of the ethyl ester of etomidate.[1][2]
^Chen Y, Hu X, Hao X, Liu J, Zhang X, Wang M, et al. (September 2025). "Identification of iso-butomidate as a novel etomidate analog: Simultaneous determination of seven etomidate-type new psychoactive substances and etomidate acid in human hair by HPLC-MS/MS". Toxicologie Analytique et Clinique. doi:10.1016/j.toxac.2025.09.003.
^Zhang X, Wang M, Chen Y, Dai Y, Zhou X, Sun Y, et al. (2025). "Identification and characterization of iso-butomidate metabolites in HLMs and mice by Liquid chromatography-high resolution mass spectrometry for drug control". SSRN. doi:10.2139/ssrn.5387249.
