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Pharmaceutical compound
CF2-Etomidate
2,2-difluoroethyl 3-(1-phenylethyl)imidazole-4-carboxylate
PubChem CID Formula C 14 H 14 F 2 N 2 O 2 Molar mass −1 3D model (JSmol )
CC(C1=CC=CC=C1)N2C=NC=C2C(=O)OCC(F)F
InChI=1S/C14H14F2N2O2/c1-10(11-5-3-2-4-6-11)18-9-17-7-12(18)14(19)20-8-13(15)16/h2-7,9-10,13H,8H2,1H3
Key:MDIFFQRDXCWIIL-UHFFFAOYSA-N
CF2-Etomidate is an anesthetic drug related to etomidate , which has been sold as a designer drug as an active ingredient in e-cigarette liquids marketed under names such as space oil or kpods . It has a 2,2-difluoroethyl ester group in place of the ethyl ester of etomidate.[ 1]
^ Bai S, Li M, Tang S, Wan S, Wu R, Chen L, Wang F, Liu S (2025). "Drug substitutes - Insights on benefits, risks, detection methods, and management strategies: a systematic review" . Frontiers in Psychiatry . 16 1600212. doi :10.3389/fpsyt.2025.1600212 PMC 12310920 PMID 40747264 .
Alcohols Barbiturates Benzodiazepines Carbamates Flavonoids Imidazoles Kava constituentsMonoureides Neuroactive steroids Nonbenzodiazepines Phenols Piperidinediones Pyrazolopyridines Quinazolinones Volatiles /gases Others/unsorted
3-Hydroxybutanal α-EMTBL AA-29504 Alogabat Avermectins (e.g., ivermectin )Bromide compounds (e.g., lithium bromide , potassium bromide , sodium bromide )Carbamazepine Chloralose Chlormezanone Clomethiazole Darigabat DEABL Deuterated etifoxine Dihydroergolines (e.g., dihydroergocryptine , dihydroergosine , dihydroergotamine , ergoloid (dihydroergotoxine) )DS2 Efavirenz Etazepine Etifoxine Fenamates (e.g., flufenamic acid , mefenamic acid , niflumic acid , tolfenamic acid )Fluoxetine Flupirtine Hopantenic acid KRM-II-81 Lanthanum Lavender oil Lignans (e.g., 4-O-methylhonokiol , honokiol , magnolol , obovatol )Loreclezole Menthyl isovalerate (validolum) Monastrol Nicotinic acid Nicotinamide Org 25,435 Phenytoin Propanidid Retigabine (ezogabine) Safranal Seproxetine Stiripentol Sulfonylalkanes (e.g., sulfonmethane (sulfonal) , tetronal , trional )Terpenoids (e.g., borneol )Topiramate Valerian constituents (e.g., isovaleric acid , isovaleramide , valerenic acid , valerenol )
