Triethylene glycol dimethyl ether

Triethylene glycol dimethyl ether
Names
	Preferred IUPAC name 2,5,8,11-Tetraoxadodecane
	Other names Triglyme; 1,2-Bis(2-methoxyethoxy)ethane
Identifiers
CAS Number	112-49-2 ;
3D model (JSmol)	Interactive image;
Abbreviations	TEGDME
ChEBI	CHEBI:31967;
ChemSpider	13835222;
ECHA InfoCard	100.003.616
PubChem CID	8189;
UNII	32YXG88KK0 ;
CompTox Dashboard (EPA)	DTXSID8026224 ;
	InChI InChI=1S/C8H18O4/c1-9-3-5-11-7-8-12-6-4-10-2/h3-8H2,1-2H3 Key: YFNKIDBQEZZDLK-UHFFFAOYSA-N;
	SMILES COCCOCCOCCOC;
Properties
Chemical formula	C8H18O4
Molar mass	178.228 g·mol−1
Appearance	Colorless liquid
Density	0.986 g/cm3
Melting point	−45 °C (−49 °F; 228 K)
Boiling point	216 °C (421 °F; 489 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Triethylene glycol dimethyl ether (also called triglyme) is a glycol ether and solvent. It is used as a reaction medium in organic chemistry,^[1] as well as a component of certain brake fluids, paints, adhesives, and paint strippers.^[2]^[3]^[4]

References

^ Fieser, Louis Frederick; Fieser, Mary (1967). Reagents for Organic Synthesis. Wiley. pp. 239, 1110. Retrieved 2025-10-13.
^ Wilson, Kimberly; Tome, Alice; Narayan, Tulika (9 September 2009). "Actual and Potential Uses of Fourteen Selected Glymes". Abt Associates (memorandum). Retrieved 13 October 2025.
^ "Ethylene Glycol Ethers; Significant New Use Rule". Environmental Protection Agency. 16 December 2014. 79 FR 74639. Retrieved 13 October 2025.
^ Tang, Shaokun; Zhao, Hua (2014). "Glymes as Versatile Solvents for Chemical Reactions and Processes: from the Laboratory to Industry". RSC Advances. 4 (22) 11251. doi:10.1039/C3RA47191H.

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[Fieser1967-1] Fieser, Louis Frederick; Fieser, Mary (1967). Reagents for Organic Synthesis. Wiley. pp. 239, 1110. Retrieved 2025-10-13.

[Abt2009-2] Wilson, Kimberly; Tome, Alice; Narayan, Tulika (9 September 2009). "Actual and Potential Uses of Fourteen Selected Glymes". Abt Associates (memorandum). Retrieved 13 October 2025.

[EPA-SNUR2014-3] "Ethylene Glycol Ethers; Significant New Use Rule". Environmental Protection Agency. 16 December 2014. 79 FR 74639. Retrieved 13 October 2025.

[TangZhao2014-4] Tang, Shaokun; Zhao, Hua (2014). "Glymes as Versatile Solvents for Chemical Reactions and Processes: from the Laboratory to Industry". RSC Advances. 4 (22) 11251. doi:10.1039/C3RA47191H.

[1]

[2]

[3]

[4]

See also

References