Sertraline
Guā-māu
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| Trade names | Zoloft (左洛復), 彼邁樂 , Lustral téng[1] |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a697048 |
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| Routes of administration | kháu-ho̍k |
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| Bioavailability | 44% |
| Protein binding | 98.5% |
| Metabolism | koaⁿ-chōng[2] |
| Elimination half-life | ~23-26 tiám-cheng (Ke hoa̍t-sèng ê tāi-siā sán-bu̍t Norsertraline sī 66 tiám-cheng)[3][4] |
| Excretion | jiō-e̍k |
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| Formula | C17H17Cl2N |
| Molar mass | 306.229 g/mol |
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Sertraline mā kiò chò Sià-khiok-lîm (舍曲林) , ia̍h ū Zoloft ê siong-phín miâ, sī chi̍t chióng sóan-te̍k-sèng huih-chheng-sò͘ chài-liap-chhú ek-chè-chè lūi ê khòng ek-ut io̍h-bu̍t, tī 1991 nî iû Pfizer chè-io̍h kong-su hoat-bêng.
Sèng-chit
[siu-kái | kái goân-sí-bé]Sertraline sī pe̍h-sek, bâ-bui iûⁿ î chúi ê kiat-chiⁿ.
- ↑ drugs.com drugs.com international Sertraline Page accessed May 11, 2015
- ↑ Obach RS, Cox LM, Tremaine LM (2005). "Sertraline is metabolized by multiple cytochrome P450 enzymes, monoamine oxidases, and glucuronyl transferases in human: an in vitro study". Drug Metab. Dispos. 33 (2): 262–70. doi:10.1124/dmd.104.002428. PMID 15547048.
- ↑ Sertraline FDA Label. http://www.fda.gov/ohrms/dockets/ac/04/briefing/4006b1_06_zoloft-label.pdf
- ↑ Brunton L, Chabner B, Knollman B. Goodman and Gilman’s The Pharmacological Basis of Therapeutics, Twelfth Edition. McGraw Hill Professional; 2010.