SUN5

SUN5
Identifikatori
Aliasi	SUN5
Vanjski ID-jevi	OMIM: 613942 MGI: 1923657 HomoloGene: 12640 GeneCards: SUN5
Lokacija gena (čovjek)
Hrom.	Hromosom 20 (čovjek)
Kraj	33,004,433 bp
Lokacija gena (miš)
Hrom.	Hromosom 2 (miš)
Kraj	153,713,004 bp
Ontologija gena
Molekularna funkcija	• protein-membrane adaptor activity; • molekularna funkcija;
Ćelijska komponenta	• integral component of membrane; • membrana; • jedro; • nuclear inner membrane; • sperm connecting piece; • Golđijev aparat; • nuclear envelope; • meiotic nuclear membrane microtubule tethering complex;
Biološki proces	• nuclear envelope organization; • Spermatogeneza; • Ćelijska diferencijacija; • spermatid development;
	Izvori:Amigo / QuickGO
Ortolozi
	140732
	76407
	ENSG00000167098
	ENSMUSG00000027480
	Q8TC36
	Q9DA32
	NM_080675
	NM_029599; NM_001305048
	NP_542406
	NP_001291977; NP_083875
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

SUN domen-sadržavajući protein 5, ranije znan i kao sperma-pridruženi antigen 4-oliki protein (SPAGL4), je protein koji je kod ljudi kodiran genom SUN5.^[5]^[6]^[7]

Aminokiselinska sekvenca

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

10	20	30	40	50
MPRSSRSPGD	PGALLEDVAH	NPRPRRIAQR	GRNTSRMAED	TSPNMNDNIL
LPVRNNDQAL	GLTQCMLGCV	SWFTCFACSL	RTQAQQVLFN	TCRCKLLCQK
LMEKTGILLL	CAFGFWMFSI	HLPSKMKVWQ	DDSINGPLQS	LRLYQEKVRH
HSGEIQDLRG	SMNQLIAKLQ	EMEAMSDEQK	MAQKIMKMIH	GDYIEKPDFA
LKSIGASIDF	EHTSVTYNHE	KAHSYWNWIQ	LWNYAQPPDV	ILEPNVTPGN
CWAFEGDRGQ	VTIQLAQKVY	LSNLTLQHIP	KTISLSGSLD	TAPKDFVIYG
MEGSPKEEVF	LGAFQFQPEN	IIQMFPLQNQ	PARAFSAVKV	KISSNWGNPG
FTCLYRVRVH	GSVAPPREQP	HQNPYPKRD

Reference

1 2 3 GRCh38: Ensembl release 89: ENSG00000167098 - Ensembl, maj 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027480 - Ensembl, maj 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Tarnasky H, Gill D, Murthy S, Shao X, Demetrick DJ, van der Hoorn FA (Oct 1998). "A novel testis-specific gene, SPAG4, whose product interacts specifically with outer dense fiber protein ODF27, maps to human chromosome 20q11.2". Cytogenet Cell Genet. 81 (1): 65–7. doi:10.1159/000014990. hdl:1807.1/829. PMID 9691178. S2CID 30497041.
↑ Shao X, Tarnasky HA, Lee JP, Oko R, van der Hoorn FA (Jul 1999). "Spag4, a novel sperm protein, binds outer dense-fiber protein Odf1 and localizes to microtubules of manchette and axoneme". Dev Biol. 211 (1): 109–23. doi:10.1006/dbio.1999.9297. PMID 10373309.
↑ "Entrez Gene: SPAG4L sperm associated antigen 4-like".

Dopunska literatura

Kierszenbaum AL, Tres LL (2003). "Bypassing natural sperm selection during fertilization: the azh mutant offspring experience and the alternative of spermiogenesis in vitro". Mol. Cell. Endocrinol. 187 (1–2): 133–8. doi:10.1016/S0303-7207(01)00692-X. PMID 11988320. S2CID 27072243.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Xing XW, Li LY, Fu JJ, et al. (2003). "[Cloning of cDNA of TSARG4, a human spermatogenesis related gene]". Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao. 35 (3): 283–8. PMID 12621555.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000167098 - Ensembl, maj 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027480 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9691178-5] Tarnasky H, Gill D, Murthy S, Shao X, Demetrick DJ, van der Hoorn FA (Oct 1998). "A novel testis-specific gene, SPAG4, whose product interacts specifically with outer dense fiber protein ODF27, maps to human chromosome 20q11.2". Cytogenet Cell Genet. 81 (1): 65–7. doi:10.1159/000014990. hdl:1807.1/829. PMID 9691178. S2CID 30497041.

[pmid10373309-6] Shao X, Tarnasky HA, Lee JP, Oko R, van der Hoorn FA (Jul 1999). "Spag4, a novel sperm protein, binds outer dense-fiber protein Odf1 and localizes to microtubules of manchette and axoneme". Dev Biol. 211 (1): 109–23. doi:10.1006/dbio.1999.9297. PMID 10373309.

[entrez-7] "Entrez Gene: SPAG4L sperm associated antigen 4-like".

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