Ribonucleoside
A ribonucleoside is a type of nucleoside including ribose as a component.[1] They are analogous to the nucleosides that, along with a phosphate group, form nucleotides that are the functional units of DNA; however, ribonucleosides are principal components of RNA. These form ribonucleotides with the addition of a phosphate group, which chain to form a molecule of RNA.
Deoxyribonucleosides (or simply nucleosides) are synthesised from ribonucleosides through a series of reactions.[2] It is possible for ribonucleosides to be converted to their deoxy form through a reaction catalysed by ribonucleoside disphosphate reductase.[3] The enzyme itself provides reducing equivalents by having its sulfhydryl groups oxidised through the course of the reaction.
One example of a ribonucleoside is cytidine.[4]
References
[edit]- ^ Ribonucleosides at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- ^ Henderson, J. Frank; Paterson, A.R.P. (1973), "ENZYMATIC REDUCTION OF RIBONUCLEOTIDES", Nucleotide Metabolism, Elsevier, pp. 244–263, doi:10.1016/b978-0-12-340550-0.50024-1, ISBN 978-0-12-340550-0, retrieved 2025-10-15
- ^ Bhagavan, N.V. (2002), "Nucleotide Metabolism", Medical Biochemistry, Elsevier, pp. 615–644, doi:10.1016/b978-012095440-7/50029-9, ISBN 978-0-12-095440-7, retrieved 2025-10-15
- ^ "Ribonucleoside". Science Direct. 2007. Retrieved February 3, 2022.
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