Daniel MacArthur
Daniel MacArthur | |
|---|---|
| Citizenship | Australian |
| Education | University of Sydney |
| Known for | Genome Aggregation Database, 1000 Genomes Project |
| Awards | American Society of Human Genetics Early Career Award, European Society of Human Genetics Award |
Daniel Geoffrey MacArthur is an Australian geneticist who is currently serving as the director of the Centre for Population Genomics (CPG) in Darlinghurst, Australia.[1]
Education and career
[edit]MacArthur completed his undergraduate and PhD in biomedical science at the University of Sydney before moving to postdoctoral studies at the Wellcome Trust Sanger Institute in Cambridge, UK.[1] During this time, MacArthur was involved in the 1000 Genomes Project.[2] He then took up a faculty position at Harvard Medical School, Massachusetts General Hospital, and the Broad Institute of MIT and Harvard in Boston to build a new research team in a recently established department led by Mark Daly.[3] During his time at the Broad Institute, led the development of the Exome Aggregation Consortium (ExAC) - later known as The Genome Aggregation Database (gnomAD) - in 2014.[4] gnomAD is now the world's largest publicly available collection of human DNA variation, spanning over 800,000 individuals.[5]
MacArthur left the Broad Institute as he moved to Australia to lead the CPG, a joint initiative between the Garvan Institute of Medical Research and the Murdoch Children's Research Institute, in 2020.[6]
Awards
[edit]- American Society of Human Genetics Early Career Award (2017)[7]
- European Society of Human Genetics Award (2025)[3]
References
[edit]- ^ a b "Our Leaders - Centre for Population Genomics". Centre for Population Genomics. Retrieved June 24, 2025.
- ^ MacArthur, Daniel G.; Balasubramanian, Suganthi; Frankish, Adam; Huang, Ni; Morris, James; Walter, Klaudia; Jostins, Luke; Habegger, Lukas; Pickrell, Joseph K.; Montgomery, Stephen B.; Albers, Cornelis A.; Zhang, Zhengdong D.; Conrad, Donald F.; Lunter, Gerton; Zheng, Hancheng (2012-02-17). "A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes". Science. 335 (6070): 823–828. doi:10.1126/science.1215040. ISSN 0036-8075. PMC 3299548. PMID 22344438.
- ^ a b "Daniel MacArthur - ESHG Conference 2025". ESHG. Vienna, Austria. Retrieved June 24, 2025.
- ^ "About gnomAD". gnomAD. Retrieved June 24, 2025.
- ^ Baxter, Samantha; Singer-Berk, Moriel; Russell, Kathryn; Amin, Mutaz; Glaze, Carmen; Grant, Riley; Lee, Josephine; Watts, Nick; Wilson, Michael; Rehm, Heidi; O'Donnell-Luria, Anne (2024-01-01). "P138: Evaluating the impact of gnomAD v4 on genetic prevalence estimates*". Genetics in Medicine Open. 2024 ACMG Annual Clinical Genetics Meeting. 2 101035. doi:10.1016/j.gimo.2024.101035. ISSN 2949-7744.
- ^ "Professor Daniel MacArthur". Garvan Institute. Darlinghurst, NSW. Retrieved June 24, 2025.
- ^ "ASHG Past Award Recipients". American Society of Human Genetics. Rockville, Maryland. Retrieved June 24, 2025.